Lorazepam or diazepam in paediatric status epilepticus
نویسندگان
چکیده
منابع مشابه
A comparison of lorazepam and diazepam as initial therapy in convulsive status epilepticus.
BACKGROUND Previous trials have suggested lorazepam may be superior to diazepam as first-line treatment of convulsive status epilepticus (CSE), with improved seizure outcome, and a lower incidence of side-effects. Many published guidelines however still recommend diazepam. AIM To compare the efficacy, safety and cost of lorazepam compared to diazepam, in adults with CSE. DESIGN Retrospectiv...
متن کاملLorazepam vs diazepam for pediatric status epilepticus: a randomized clinical trial.
IMPORTANCE Benzodiazepines are considered first-line therapy for pediatric status epilepticus. Some studies suggest that lorazepam may be more effective or safer than diazepam, but lorazepam is not Food and Drug Administration approved for this indication. OBJECTIVE To test the hypothesis that lorazepam has better efficacy and safety than diazepam for treating pediatric status epilepticus. ...
متن کاملA comparison of lorazepam, diazepam, and placebo for the treatment of out-of-hospital status epilepticus.
BACKGROUND It is uncertain whether the administration of benzodiazepines by paramedics is an effective and safe treatment for out-of-hospital status epilepticus. METHODS We conducted a randomized, double-blind trial to evaluate intravenous benzodiazepines administered by paramedics for the treatment of out-of-hospital status epilepticus. Adults with prolonged (lasting five minutes or more) or...
متن کاملComparative audit of intravenous lorazepam and diazepam in the emergency treatment of convulsive status epilepticus in children
There is little evidence on which to judge the optimal treatment for convulsive status epilepticus (CSE) in children. This study compares the effect of intravenous (iv) lorazepam with iv diazepam as the first line of treatment of CSE. We studied all children with prolonged seizures arriving in the Accident and Emergency (A&E) Department in two separate periods. In the first 6-month period iv di...
متن کاملReview: lorazepam provides the best control for status epilepticus.
and commentary also appear in ACP Journal Club and a modified version of the abstract appears in Evidence-Based Nursing. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . For correspondence: Dr K Prasad, All India Institute of Medical Sciences, New Delhi, India. [email protected] Source of funding: no external f...
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ژورنال
عنوان ژورنال: Emergency Medicine Journal
سال: 2006
ISSN: 1472-0205,1472-0213
DOI: 10.1136/emj.2006.037606